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鼠抗人CD61單克隆抗體現(xiàn)貨供應
單克隆抗體是由單一B細胞克隆產(chǎn)生的高度均一、僅針對某一特定抗原表位的抗體。通常采用雜交瘤技術來制備,雜交瘤(hybridoma)抗體技術是在細胞融合技術的基礎上,將具有分泌特異性抗體能力的致敏B細胞和具有無限繁殖能力的骨髓瘤細胞融合為B細胞雜交瘤。
CD61是一種110 kDa膜糖蛋白,也稱為整合素β3鏈或GPIIIa。CD61可與整合素αV鏈(CD51)或整合素βIIb鏈(CD41,GPIIb)結合,形成細胞戰(zhàn)術素、纖維連接蛋白、纖維蛋白原、層粘連蛋白、基質金屬蛋白酶-2、骨橋蛋白、骨調節(jié)蛋白、纖溶酶原、血小板反應蛋白、玻璃體凝集素和血管性血友病因子的異二聚體受體,一些成纖維細胞、一些活化的白細胞和腫瘤細胞。GPllb llla(CD41-CD61)在血小板和巨核細胞潛能細胞中的分布受到限制,是血小板聚集所必需的。
Catalog Number: XF-22153A
Size: 100ug: 100ug 1mg/ml
Source: Mouse
Purification method: Purified by protein-A affinity chromatography
Isotype: Mouse IgG1 kappa
Storage: PBS with 0.1% sodium azide.Store at 2-8°C.
Immunogen: N/A
Full name: integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Calculated molecular weight: 788 aa, 87 kDa
Gene symbol: ITGB3
Synonyms: CD61, GP3A, GPIIIa, Integrin beta 3, ITGB3
Species Specificity: Human, Non-human primates;other species not tested
Positive FC detected in: Human peripheral blood platelets
Recommended dilution: This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.